动物实验低压氧舱

产品描述：

动物实验低压氧舱用于模拟低压氧高原环境，压力可以根据需要自行设置，可模拟海拔高度高达12000米，适用于更多的鼠笼或中小型动物如犬、猴、兔、鼠等。

整个实验装置由动物舱体、真空系统、监测及控制系统构成。设备的自动化程度高，无须专人守候，可长期持续一个月运行。

产品特点：

人性化操作

• 采用10英寸触摸屏，人性化界面设计，操作简便。
• 两种控制方式：自动、手动，断电可操控；具有传感器组件及机械表双重监测功能。设备自动化程序设计，无须专人守候，可长期持续运转。
• 实时显示海拔和氧分压动态变化曲线。
• 实验过程数据可导出csv格式保存到U盘中，在电脑中读取分析。
• 可根据客户实验需求，订制实验环境及配套其他相关实验设备。
• 配备动物低压专用水瓶，防止在负压环境中，水滴漏速过快。

操作安全放心

• 配备自动换气功能，符合动物饲养规范。
• 提供多方位报警功能（温度、湿度、压力、氧浓度 上/下限），防止出现安全隐患。配备渐开手轮式舱门，降低因为误操作造成的伤害。
• 舱体采用透明厚亚克力材质，方便研究人员观察实验动物情况。
• 配备气体缓冲器，减小、甚至消除了细股急流气体对小动物的影响。
• 配备多级空气过滤器，确保动物舱内实验环境空气不会收到污染。
• 舱体模拟承受力分析，确保这种结构足够安全。

 

 

参数显示/功能全

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

拓展及特殊定制：

动物生理指标监测

可实现的监测指标：心电图、心率、体温、血压、呼吸、血氧饱和度；

呼吸代谢监控功能

采血给药功能

视频监测功能

动物低氧跑台装置

低氧强迫游泳装置

温控功能

恒温功能，温度可控制，室温-40℃；

低温功能，4℃，温度可控制，室温-4℃；

可定制其它功能

应用领域

高原医学研究、肺水肿、脑水肿、肺动脉高压等疾病研究

型号说明

名称	型号	说明
动物低压氧舱 标准版	ProOx-810	可以摆放2个大鼠笼/4个小鼠笼
动物低压氧舱 恒温版	ProOx-811	可以摆放2个大鼠笼/4个小鼠笼，同时加上恒温功能
动物低压氧舱 大容量版	ProOx-810L	可以摆放4个大鼠笼/8个小鼠笼（可叠加）
动物低压氧舱 大容量版+恒温	ProOx-811L	可以摆放4个大鼠笼/8个小鼠笼（可叠加），同时加上恒温功能
动物低压氧舱 基础款	ProOx-830	可以摆放1个大鼠笼/2个小鼠笼

使用客户名单

相关文献

[1]Ma Jinqiu,Wang Chenyun,Sun Yunbo,Pang Lulu,Zhu Siqing,Liu Yijing,Zhu Lin,Zhang Shouguo,Wang Lin,Du Lina. Comparative study of oral and intranasal puerarin for prevention of brain injury induced by acute high-altitude hypoxia.[J] International Journal of Pharmaceutics,2020,591

[2]Guijuan Chen,Kang Cheng,Yun Niu,Li Zhu,Xueting Wang.Epicatechin gallate prevents inflammatory response in hypoxia-activated microglia and cerebral edema by inhibiting NF-κB signaling.[J]Archives of Biochemistry and Biophysics ,Volume 729, 109393;

[3]Yapeng,LuPanpanChang,WangwangDing,JiangpeiBian,DanWang,XuetingWang,QianqianLuo,XiaomeiWu,LiZhu.Pharmacological inhibition of mitochondrial division attenuates simulated high-altitude exposure-induced cerebral edema in mice: Involvement of inhibition of the NF-κB signaling pathway in glial cells.[J] European Journal of Pharmacology,Volume 929,2022,175137

[4]Jun-Yu Wei, Miao-Yue Hu, Xiu-Qi Chen, Feng-Ying Lei, Jin-Shuang Wei, Jie Chen, Xuan-Kai Qin & Yuan-Han Qin .Rosiglitazone attenuates hypoxia-induced renal cell apoptosis by inhibiting NF-κB signaling pathway in a PPARγ-dependent manner, [J] European Journal of Pharmacology,Renal Failure, 44:1, 2056-2065

[5]Yilan Wang, Zherui Shen, Caixia Pei, Sijing Zhao, Nan Jia, Demei Huang, Xiaomin Wang, Yongcan Wu, Shihua Shi, Yacong He, Zhenxing Wang,Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling, [J] Biomedicine & Pharmacotherapy, Volume 156, 2022,113982

[6]Fang Zhao, Yan Meng, Yue Wang, Siqi Fan, Yu Liu,Xiangfeng Zhang, Chenyang Ran, Hongxin Wang and Meili Lu,Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway.[J] Frontiers in Pharmacology,10.3389/fphar.2022.920977

[7]Jing Zhang , Jian-Zhong Jiang , Jun Xu , Chen-Yu Xu , Shan Mao , Ying Shi , Wei Gu , Chun-Fang Zou , Yue-Ming Zhao , Liang Ye.”Identification of Novel Biomarkers for Abdominal Aortic Aneurysm Promoted by Obstructive Sleep Apnea”[J]Annals of Vascular Surgery, Available online 2 February 2023

[8]Zhang, C., Sun, Y., Guo, Y. et al. “JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension. “[J].Cell Death Discov. 9, 98 (2023).

[9]Zhang, L., Liu, X., Wei, Q. et al. “Arginine attenuates chronic mountain sickness in rats via microRNA-144-5p. “[J]. Mamm Genome 34, 76–89 (2023).

[10]Yanhong Pei a b, Lifei Huang c, Tong Wang c, Qinhan Yao a, Yanrong Sun a, Yan Zhang a, Xiaomei Yang a, Jiliang Zhai d, Lihua Qin a, Jiajia Xue c, Xing Wang c, Hongquan Zhang a b, Junhao Yan.”Bone marrow mesenchymal stem cells loaded into hydrogel/nanofiber composite scaffolds ameliorate ischemic brain injury. materialstoday ADVANCES, Volume 17, March 2023, 100349.

[11]Ma Jinqiu,Wang Chenyun,Sun Yunbo,Pang Lulu,Zhu Siqing,Liu Yijing,Zhu Lin,Zhang Shouguo,Wang Lin,Du Lina. “Comparative study of oral and intranasal puerarin for prevention of brain injury induced by acute high-altitude hypoxia” . [J] International Journal of Pharmaceutics,2020,591

[12]Jun-Yu Wei, Miao-Yue Hu, Xiu-Qi Chen, Feng-Ying Lei, Jin-Shuang Wei, Jie Chen, Xuan-Kai Qin & Yuan-Han Qin .”Rosiglitazone attenuates hypoxia-induced renal cell apoptosis by inhibiting NF-κB signaling pathway in a PPARγ-dependent manner” . [J]. European Journal of Pharmacology,Renal Failure, 44:1, 2056-2065

[13]Yilan Wang, Zherui Shen, Caixia Pei, Sijing Zhao, Nan Jia, Demei Huang, Xiaomin Wang, Yongcan Wu, Shihua Shi, Yacong He, Zhenxing Wang,”Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling” . [J]. Biomedicine & Pharmacotherapy, Volume 156, 2022,113982

[14]Yanfei Zhang, Jinyu Fang, Yingyue Dong, Huiru Ding, Quancheng Cheng, Huaicun Liu, Guoheng Xu, Weiguang Zhang“High-Altitude Hypoxia Exposure Induces Iron Overload and Ferroptosis in Adipose Tissue.” [J]. Antioxidants 2022, 11, 2367.

[15]Wan-ping Yang, Mei-qi Li, Jie Ding, Jia-yan Li, Gang Wu, Bao Liu, Yu-qi Gao, Guo-hua Wang, Qian-qian Luo. “High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen.” [J]. bioRxiv preprint, 2023.03.23.533972

 

 

参考：

高原疾病介绍

不同的海拔高度大气压和氧分压的变化对比

 

*我公司可提供3Q验证，根据客户的特殊应用、特殊需求提供功能定制服务，也可以提供相关的实验服务，详情请来电咨询。